UMR 8060
The SEISAD Team develops projects aimed at elaborating processes and tools for the early detection of pathological signals using chemical and analytical methodologies. The main prospections are related to:
(i) new methodologies of synthesis and supported catalysis in mini – and continuous microflow reactors, synthesis of libraries of molecules as ligands of proteins, development of new radio-labelling methodologies for imaging ;
(ii) electrochemical sensors for biological systems and for screening biological markers, molecular materials for electroanalysis and electrocatalysis, microelectrochemical patterning of surfaces using scanning electrochemical microscopy, label-free electrochemical detection of microRNAs ;
(iii) preparation of targeted optical and MR imaging agents, development of molecular magnetic resonance imaging MRI methods & functional imaging methods for the characterization and therapeutic follow-up of cancer in preclinics ;
(iv) characterization of new nano-supports and selective objects : peptide nanotubes, aptamers, nanobodies, design and characterization of original biocompatible nano-objects and quantitative characterization of their non-covalent interactions, development of miniaturized total analysis systems for applications ranging from environmental control to in-vitro medical diagnosis.